1,8-Cineole, a TRPM8 Agonist, is a Novel Natural Antagonist of Human TRPA1
نویسندگان
چکیده
منابع مشابه
1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1
BACKGROUND Essential oils are often used in alternative medicine as analgesic and anti-inflammatory remedies. However, the specific compounds that confer the effects of essential oils and the molecular mechanisms are largely unknown. TRPM8 is a thermosensitive receptor that detects cool temperatures and menthol whereas TRPA1 is a sensor of noxious cold. Ideally, an effective analgesic compound ...
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ژورنال
عنوان ژورنال: Molecular Pain
سال: 2012
ISSN: 1744-8069,1744-8069
DOI: 10.1186/1744-8069-8-86